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Patients receiving sitagliptin with metformin immediate-release and glimepiride had significant improvements in A1C and FPG compared to patients receiving placebo with metformin immediate-release and glimepiride (Table 11), with mean reductions from baseline relative to placebo in A1C of -0.9% and in FPG of -21 mg/dL

"A substantial number of patients still face an unmet need, especially when preventive drugs prove ineffective," writes a team of scientists led by neurologist Simone Braca

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Cardiovascular and Renal Benefits Beyond glycemic control, GLP-1 receptor agonists have demonstrated significant cardiovascular and renal benefits

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